Linked Life Data

19398322

Source:http://linkedlifedata.com/resource/pubmed/id/19398322

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2009-7-17
pubmed:abstractText
Recent advances in molecular biology elucidate that tumor markers play an important role in diagnosis, prognosis and providing insights into the etiology of cancer. Widespread use of tumor markers in healthcare will ultimately depend upon the detection of many tumor markers with high selectivity and sensitivity. This goal has not been obtained with conventional methods which are time-consuming, have poor precision, or experience difficulty in realizing automation. Recently, much attention has been paid to the use of electrochemical immunosensors for the detection of tumor markers due to their high sensitivity, easy miniaturization and automation. This brief review focuses on the current developments, challenges, and trends of electrochemical immunosensors for tumor markers based on protein chips. Whereafter, the recent applications of nanomaterials in tumor marker immunoassays are reviewed. We also introduce some of our group's research works of novel electrochemical immunosensors for the determination of tumor markers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1873-4235
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3399-411
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Protein chips and nanomaterials for application in tumor marker immunoassays.
pubmed:affiliation
Department of Chemistry, CAM & IBS, Fudan University, Shanghai, 200433, PR China.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't