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pubmed:abstractText |
In the rural zone of Niakhar in Senegal, the first therapeutic failures for chloroquine (CQ) were observed in 1992. In 2003, the national policy regarding first-line treatment of uncomplicated malaria was modified, replacing CQ by a transitory bi-therapy amodiaquine/sulphadoxine-pyrimethamine (AQ/SP), before the implementation of artemisinin-based combination therapy (ACT) in 2006. The aims of the study were to assess the evolution of anti-malarial prescriptions in three health care facilities between 1992 and 2004, in parallel with increasing CQ resistance in the region.
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pubmed:affiliation |
Unité de recherche Santé de la mère et de l'enfant en milieu tropical, IRD UR010, Université Paris Descartes, 4 av de l'Observatoire, 75270 Paris cedex 06, France. munier_aline@yahoo.fr
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