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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-6-8
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pubmed:abstractText |
We describe a novel ultrasensitive cell-based immunocytotoxicity assay for detecting Clostridium difficile toxin A and B. The assay is simple to perform with a turnaround time of approximately 3 h . It is particularly sensitive in detecting TcdA at a level less then 1 pg/ml. Using this assay, we were able to detect the presence of C. difficile toxins in the fecal and serum specimens of experimentally infected piglets.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-10872133,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-11821511,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-12574241,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-15350524,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-16966605,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-17116920,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-17918076,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-18971494,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-18990232,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-231071,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-2911306,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-3666963,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-9040006,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19393695-9509270
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1872-8359
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
78
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
97-100
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pubmed:dateRevised |
2010-9-27
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pubmed:meshHeading |
pubmed-meshheading:19393695-Animals,
pubmed-meshheading:19393695-Antibodies, Bacterial,
pubmed-meshheading:19393695-Bacterial Toxins,
pubmed-meshheading:19393695-Biological Assay,
pubmed-meshheading:19393695-Cell Line,
pubmed-meshheading:19393695-Clostridium difficile,
pubmed-meshheading:19393695-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:19393695-Cytotoxins,
pubmed-meshheading:19393695-Sensitivity and Specificity,
pubmed-meshheading:19393695-Swine
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pubmed:year |
2009
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pubmed:articleTitle |
An ultrasensitive rapid immunocytotoxicity assay for detecting Clostridium difficile toxins.
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pubmed:affiliation |
Division of Infectious Diseases, Department of Biomedical Sciences, Tufts University Cummings School of Veterinary Medicine, North Grafton, Massachusetts 01536, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies,
Research Support, N.I.H., Extramural
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