Linked Life Data

19393650

Source:http://linkedlifedata.com/resource/pubmed/id/19393650

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
16
pubmed:dateCreated
2009-8-21
pubmed:abstractText
Systemic AA-amyloidosis is a complication of chronic inflammatory diseases and the fibril protein AA derives from the acute phase reactant serum AA. AA-amyloidosis can be induced in mice by an inflammatory challenge. The lag phase before amyloid develops can be dramatically shortened by administration of a small amount of amyloid fibrils. Systemic AA-amyloidosis is transmissible in mice and may be so in humans. Since transmission can cross species barriers it is possible that AA-amyloidosis can be induced by amyloid in food, e.g. foie gras. In mice, development of AA-amyloidosis can also be accelerated by other components with amyloid-like properties. A new possible risk factor may appear with synthetically made fibrils from short peptides, constructed for tissue repair.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1873-3468
pubmed:author
pubmed:issnType
Electronic
pubmed:day
20
pubmed:volume
583
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2685-90
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Serum amyloid A and protein AA: molecular mechanisms of a transmissible amyloidosis.
pubmed:affiliation
Division of Cell Biology, Diabetes Research Centre, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden. Per.Westermark@genpat.uu.se
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't