19392577

Source:http://linkedlifedata.com/resource/pubmed/id/19392577

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0039796, umls-concept:C1099354, umls-concept:C1704419
pubmed:issue	5
pubmed:dateCreated	2009-4-27
pubmed:abstractText	RNA interference (RNAi) is a promising new therapeutic modality. By acting at the mRNA level, RNAi circumvents the druggability issue associated with many disease-driven genes. The lack of safe and effective methods to deliver RNAi therapeutics remains the primary technical hurdle that prevents full utilization of the potential of RNAi therapy.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101125414
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	1744-7682
pubmed:author	pubmed-author:LiLeimingL, pubmed-author:ShenYuY
pubmed:issnType	Electronic
pubmed:volume	9
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	609-19
pubmed:meshHeading	pubmed-meshheading:19392577-Animals, pubmed-meshheading:19392577-Drug Delivery Systems, pubmed-meshheading:19392577-Gene Targeting, pubmed-meshheading:19392577-Humans, pubmed-meshheading:19392577-Neoplasms, pubmed-meshheading:19392577-RNA, Small Interfering, pubmed-meshheading:19392577-Technology, Pharmaceutical
pubmed:year	2009
pubmed:articleTitle	Overcoming obstacles to develop effective and safe siRNA therapeutics.
pubmed:affiliation	siRNA Therapeutics, Abbott Laboratories, Abbott Park, IL 60031, USA.
pubmed:publicationType	Journal Article, Review