Linked Life Data

19391487

Source:http://linkedlifedata.com/resource/pubmed/id/19391487

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-4-27
pubmed:abstractText
Accidental discovery of androgen receptor (AR) expression in high-grade salivary gland cancer led to evaluation of that finding. In this study we evaluated the immunohistochemical expression of AR in a series of 37 formalin-fixed, paraffin-embedded malignant salivary gland tumors using two commercially available antibodies. Nuclear immunoreactivity for AR was demonstrated in 3 of 4 salivary duct carcinomas, 2 of 7 adenocarcinomas NOS and 1 of 2 carcinoma ex pleomorphic adenoma for both antibodies. Expression of AR was evaluated semiquantatively according to Dako ER/PR pharmDx scoring guidelines. All positive cases came from male patients. There was no immunoreactivity seen in 13 adenoid cystic carcinomas, 7 mucoepidermoid carcinomas and 4 acinic cell carcinomas. The expression of AR in high-grade salivary gland cancers suggests a possible role for AR in the clinical management of these neoplasms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1233-9687
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
205-10
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Immunohistochemical expression of androgen receptor in salivary gland cancers.
pubmed:affiliation
Department of Dental Pathology, Medical University, ?ód?. dominik.sygut@onet.pl
pubmed:publicationType
Journal Article