|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:dateCreated |
2009-4-24
|
|
pubmed:abstractText |
Brain contusions are inflammatory evolutive lesions that induce intracranial pressure increase and edema, contributing to neurological outcome. Matrix metalloproteinases (MMPs) 2 and 9 can degrade the majority of the extracellular matrix components, and are implicated in blood-brain barrier disruption and edema formation. The aim of this study was to investigate MMP-2 and MMP-9 profiles in human brain contusions using zymography.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0065-1419
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
102
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
415-9
|
|
pubmed:meshHeading |
pubmed-meshheading:19388358-Adult,
pubmed-meshheading:19388358-Brain,
pubmed-meshheading:19388358-Brain Injuries,
pubmed-meshheading:19388358-Electrophoresis,
pubmed-meshheading:19388358-Female,
pubmed-meshheading:19388358-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:19388358-Humans,
pubmed-meshheading:19388358-Male,
pubmed-meshheading:19388358-Matrix Metalloproteinase 2,
pubmed-meshheading:19388358-Matrix Metalloproteinase 9,
pubmed-meshheading:19388358-Middle Aged,
pubmed-meshheading:19388358-Pilot Projects,
pubmed-meshheading:19388358-Prospective Studies,
pubmed-meshheading:19388358-Statistics, Nonparametric,
pubmed-meshheading:19388358-Time Factors
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Brain contusions induce a strong local overexpression of MMP-9. Results of a pilot study.
|
|
pubmed:affiliation |
Neurosurgery and Neurotraumatology Research Unit, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Passeig Vail d'Hebron 119-129, 08035 Barcelona, Spain.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|
