Linked Life Data

19387031

Source:http://linkedlifedata.com/resource/pubmed/id/19387031

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-4-23
pubmed:abstractText
Since the recognition that asthma is genetically determined, enormous progress has been made to understand which genes determine disease development in interaction with each other and/or with different environmental factors. This is the result of rapid developments in techniques for genotyping and statistical analyses. However, we are only at the beginning of understanding the complex nature of asthma. Follow-up of both clinical and environmental measures in a standardized way in numerous prospective cohorts is needed to establish which sets of genes and environmental factors determine the different phenotypes of asthma. This includes differences between sex, asthma severity, asthma remission, and asthma progression. Investigation of genetic profiling and gene expression profiling may further help to better understand the underlying pathophysiologic mechanisms, taking into account the insight in the biology currently present. Only by collaborative efforts of many groups of researchers that join forces in DNA analyses will it be possible to help to develop preventive strategies for asthma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1546-3222
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
283-7
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Genetics of asthma: where are we and where do we go?
pubmed:affiliation
Department of Pulmonology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. d.s.postma@int.umcg.nl
pubmed:publicationType
Journal Article, Review