Linked Life Data

19381766

Source:http://linkedlifedata.com/resource/pubmed/id/19381766

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-4-21
pubmed:abstractText
Dopamine replacement therapy in Parkinson's disease improves motor symptoms, however some patients suffer from motor and behavioural disturbances attributable to taking doses of medication well beyond the dose required to treat their motor disabilities. Dopamine dysregulation syndrome (DDS) can be regarded as a pattern of compulsive medication use, leading to disabling motor and behavioural features. DDS, probably attributed to pulsatile overstimulation of the limbic dopaminergic system, is characterised by severe dopamine addiction and behavioural disorders such as pathological gambling (PG), hypersexuality, punding and mood swings. PG is a form of impulse control disorder (ICD), consisting of persistent and maladaptive gambling of various types, which affects personal, family and occupational activity. The treatment of the syndrome is difficult, hence a strict adherence to antiparkinson medication should be encouraged for prevention.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1590-1874
pubmed:author
pubmed:issnType
Print
pubmed:volume
29 Suppl 5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S375-6
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Dopamine agonists and therapy compliance.
pubmed:affiliation
Department of Neurology, Southern General Hospital, Glasgow, G51 4TF, UK. d.grosset@clinmed.gla.ac.uk
pubmed:publicationType
Journal Article, Review