Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1977-7-18
|
pubmed:abstractText |
Throat washings from 26 nasopharyngeal carcinoma (NPC) patients from Hong Kong and Tunisia were studied for the presence of transforming EBV. Only six (23%) were found positive which led to the hypothesis of a neutralizing factor in such salivas. The search for EBV-specific antibodies showed that NPC saliva contained neutralizing VCA and EA IgA (54 and 27% respectively) and VCA and EA IgG (73 AND 54% respectively). Both transforming and non-transforming throat washings contained virus particles as visualized by electron microscopy, but in non-transforming salivas (containing IgA and IgG) the particles were found to be clumped. Comparative study of throat washings from patients with Burkitt's lymphoma (BL); infectious mononucleosis (IM), immunodeficiencies, other cancers, and healthy subjects showed that IgA were restricted to NPC cases.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0020-7136
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
19
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
627-33
|
pubmed:dateRevised |
2007-7-24
|
pubmed:meshHeading |
pubmed-meshheading:193801-Antibodies, Viral,
pubmed-meshheading:193801-Antibody Specificity,
pubmed-meshheading:193801-Burkitt Lymphoma,
pubmed-meshheading:193801-Fluorescent Antibody Technique,
pubmed-meshheading:193801-Herpesvirus 4, Human,
pubmed-meshheading:193801-Hong Kong,
pubmed-meshheading:193801-Humans,
pubmed-meshheading:193801-Immunoglobulin A,
pubmed-meshheading:193801-Immunoglobulin G,
pubmed-meshheading:193801-Infectious Mononucleosis,
pubmed-meshheading:193801-Lymphocyte Activation,
pubmed-meshheading:193801-Microscopy, Electron,
pubmed-meshheading:193801-Nasopharyngeal Neoplasms,
pubmed-meshheading:193801-Pharynx,
pubmed-meshheading:193801-Tunisia
|
pubmed:year |
1977
|
pubmed:articleTitle |
Neutralizing EBV-specific IgA in throat washings of nasopharyngeal carcinoma (NPC) patients.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|