|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0030685,
umls-concept:C0033640,
umls-concept:C0036226,
umls-concept:C0072388,
umls-concept:C0391871,
umls-concept:C0392747,
umls-concept:C0442805,
umls-concept:C0596235,
umls-concept:C0680255,
umls-concept:C1283071,
umls-concept:C1708715,
umls-concept:C1963578,
umls-concept:C2346689
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2009-5-25
|
|
pubmed:abstractText |
An increase in cytosolic protein phosphatases (PPs) de-phosphorylates phospholamban, decreasing the Ca(2+) uptake of the sarcoplasmic reticulum (SR). The effects of PP inhibitors on cellular Ca(2+) handling were investigated.
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
1346-9843
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
73
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1133-40
|
|
pubmed:meshHeading |
pubmed-meshheading:19377265-Adrenergic beta-Agonists,
pubmed-meshheading:19377265-Animals,
pubmed-meshheading:19377265-Calcium,
pubmed-meshheading:19377265-Calcium Signaling,
pubmed-meshheading:19377265-Cyclic AMP-Dependent Protein Kinases,
pubmed-meshheading:19377265-Enzyme Inhibitors,
pubmed-meshheading:19377265-Homeostasis,
pubmed-meshheading:19377265-Isoproterenol,
pubmed-meshheading:19377265-Male,
pubmed-meshheading:19377265-Models, Animal,
pubmed-meshheading:19377265-Myocytes, Cardiac,
pubmed-meshheading:19377265-Oxazoles,
pubmed-meshheading:19377265-Patch-Clamp Techniques,
pubmed-meshheading:19377265-Proteins,
pubmed-meshheading:19377265-Rats,
pubmed-meshheading:19377265-Rats, Sprague-Dawley,
pubmed-meshheading:19377265-Sarcoplasmic Reticulum,
pubmed-meshheading:19377265-Signal Transduction
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Protein phosphatase inhibitor-1 augments a protein kinase A-dependent increase in the Ca2+ loading of the sarcoplasmic reticulum without changing its Ca2+ release.
|
|
pubmed:affiliation |
Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
