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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-4-20
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pubmed:abstractText |
Adiponectin, a key substance in metabolic syndrome, is known to have anti-inflammatory properties. The relationship between adiponectin and sepsis in vivo is unclear. In this study, the possible involvement of adiponectin in polymicrobial sepsis was investigated using adiponectin-knockout (APN-KO) mice that underwent cecal ligation and puncture (CLP) and received the peroxisome proliferator-activated receptor gamma (PPAR-gamma) that increases the plasma adiponectin concentration.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1532-7361
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
550-7
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pubmed:dateRevised |
2010-4-20
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pubmed:meshHeading |
pubmed-meshheading:19375615-Adiponectin,
pubmed-meshheading:19375615-Animals,
pubmed-meshheading:19375615-Cecum,
pubmed-meshheading:19375615-Endotoxins,
pubmed-meshheading:19375615-Hypoglycemic Agents,
pubmed-meshheading:19375615-Interleukin-6,
pubmed-meshheading:19375615-Mice,
pubmed-meshheading:19375615-Mice, Inbred C57BL,
pubmed-meshheading:19375615-Mice, Knockout,
pubmed-meshheading:19375615-PPAR gamma,
pubmed-meshheading:19375615-Sepsis,
pubmed-meshheading:19375615-Thiazolidinediones,
pubmed-meshheading:19375615-Tumor Necrosis Factor-alpha
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pubmed:year |
2009
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pubmed:articleTitle |
Adiponectin deficiency is associated with severe polymicrobial sepsis, high inflammatory cytokine levels, and high mortality.
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pubmed:affiliation |
Department of Surgery, Shiga University of Medical Science, Japan.
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pubmed:publicationType |
Journal Article
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