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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1991-11-25
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pubmed:abstractText |
A series of experiments investigated the behavioral effects of a calcium channel antagonist, nifedipine. This antagonist has facilitatory effects on learning and memory as assessed by the active and passive avoidance tests respectively. In the forced swimming test, nifedipine at a dose of 5 mg/kg had an inhibitory effect on immobilization. Finally, nifedipine (2.5 and 5.0 mg/kg) induced an anxiolytic effect in the water consumption test in a novel environment. These findings are discussed with respect to other findings in the same field and to the neurochemical changes known to be induced by calcium channel antagonists.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0767-3981
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
229-36
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1937351-Animals,
pubmed-meshheading:1937351-Avoidance Learning,
pubmed-meshheading:1937351-Behavior, Animal,
pubmed-meshheading:1937351-Drinking,
pubmed-meshheading:1937351-Male,
pubmed-meshheading:1937351-Nifedipine,
pubmed-meshheading:1937351-Rats,
pubmed-meshheading:1937351-Rats, Inbred Strains,
pubmed-meshheading:1937351-Swimming
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pubmed:year |
1991
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pubmed:articleTitle |
Behavioral effects of a calcium channel antagonist: nifedipine.
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pubmed:affiliation |
Laboratory of Pharmacology, Faculty of Medicine, Casablanca, Morocco.
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pubmed:publicationType |
Journal Article
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