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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2011-4-8
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pubmed:abstractText |
An abundance of X chromosomes in testicular germ cell tumors (TGCTs), and a candidate TGCTs susceptibility gene (TGCT1) on Xq27 highlight the potential involvement of X chromosomes in TGCT pathogenesis. However, the TGCT1 on Xq27 has so far not been identified. We hypothesized that a somatic mutation of dbl oncogene on Xq27 may play a role for the development of TGCTs.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1433-8726
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
811-5
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pubmed:meshHeading |
pubmed-meshheading:19373475-Chromosomes, Human, X,
pubmed-meshheading:19373475-Cryptorchidism,
pubmed-meshheading:19373475-DNA Mutational Analysis,
pubmed-meshheading:19373475-Genetic Predisposition to Disease,
pubmed-meshheading:19373475-Guanine Nucleotide Exchange Factors,
pubmed-meshheading:19373475-Humans,
pubmed-meshheading:19373475-Male,
pubmed-meshheading:19373475-Neoplasms, Germ Cell and Embryonal,
pubmed-meshheading:19373475-Polymorphism, Single Nucleotide,
pubmed-meshheading:19373475-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:19373475-Proto-Oncogene Proteins,
pubmed-meshheading:19373475-Testicular Neoplasms
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pubmed:year |
2009
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pubmed:articleTitle |
Mutational analysis of proto-oncogene Dbl on Xq27 in testicular germ cell tumors reveals a rare SNP in a patient with bilateral undescended testis.
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pubmed:affiliation |
Department of Urology, First and Fourth AYliated Hospital, Harbin Medical University, 150001 Harbin, Heilongjiang, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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