Source:http://linkedlifedata.com/resource/pubmed/id/19371069
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2010-6-21
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pubmed:abstractText |
Angiopterlactones A (1) and B (2), two unique lactones, and three known lactones, osmundalactone (3), osmundalin (4), and 3,5-dihydroxy-gamma-caprolactone (5), have been isolated from the rhizome of Angiopteris caudatiformis. The structures of 1 and 2 were determined by NMR and MS methods, and the structure of 2 was confirmed by X-ray crystallography. The absolute configurations of 1 and 2 were assigned by application of the CD excitation chirality method and the modified Mosher's method. Compound 1 was slightly cytotoxic against HeLa cells, with an IC(50) value of 68.8 microM, and compounds 3 and 4 showed moderate insect antifeeding activity against Plutella xylostella and Heliothis virescens.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1520-6025
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
22
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
921-4
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pubmed:meshHeading |
pubmed-meshheading:19371069-Animals,
pubmed-meshheading:19371069-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:19371069-Drug Screening Assays, Antitumor,
pubmed-meshheading:19371069-Feeding Behavior,
pubmed-meshheading:19371069-Ferns,
pubmed-meshheading:19371069-HeLa Cells,
pubmed-meshheading:19371069-Humans,
pubmed-meshheading:19371069-Inhibitory Concentration 50,
pubmed-meshheading:19371069-KB Cells,
pubmed-meshheading:19371069-Lactones,
pubmed-meshheading:19371069-Molecular Structure,
pubmed-meshheading:19371069-Moths,
pubmed-meshheading:19371069-Rhizome
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pubmed:year |
2009
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pubmed:articleTitle |
Lactones from Angiopteris caudatiformis.
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pubmed:affiliation |
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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