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rdf:type |
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lifeskim:mentions |
umls-concept:C0014406,
umls-concept:C0017262,
umls-concept:C0069676,
umls-concept:C0078058,
umls-concept:C0185117,
umls-concept:C0242184,
umls-concept:C0553662,
umls-concept:C0851285,
umls-concept:C1171892,
umls-concept:C1550315,
umls-concept:C2911684
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pubmed:issue |
6
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pubmed:dateCreated |
2009-6-10
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pubmed:abstractText |
Synovial angiogenesis, a critical determinant of juvenile idiopathic arthritis (JIA) pathogenesis, is sustained by various mediators, including vascular endothelial growth factor (VEGF) and osteopontin (OPN). We characterized the contribution of the local hypoxic environment to VEGF and OPN production by monocytic cells recruited to the synovium in JIA.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation...,
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/CD68 antigen, human,
http://linkedlifedata.com/resource/pubmed/chemical/HIF1A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoxia-Inducible Factor 1, alpha...,
http://linkedlifedata.com/resource/pubmed/chemical/Osteopontin,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/VEGFA protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0315-162X
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1318-29
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pubmed:meshHeading |
pubmed-meshheading:19369471-Adolescent,
pubmed-meshheading:19369471-Antigens, CD,
pubmed-meshheading:19369471-Antigens, Differentiation, Myelomonocytic,
pubmed-meshheading:19369471-Arthritis, Juvenile Rheumatoid,
pubmed-meshheading:19369471-Biological Markers,
pubmed-meshheading:19369471-Cell Hypoxia,
pubmed-meshheading:19369471-Cells, Cultured,
pubmed-meshheading:19369471-Child,
pubmed-meshheading:19369471-Child, Preschool,
pubmed-meshheading:19369471-Female,
pubmed-meshheading:19369471-Gene Expression,
pubmed-meshheading:19369471-Humans,
pubmed-meshheading:19369471-Hypoxia-Inducible Factor 1, alpha Subunit,
pubmed-meshheading:19369471-Male,
pubmed-meshheading:19369471-Monocytes,
pubmed-meshheading:19369471-Osteopontin,
pubmed-meshheading:19369471-RNA, Messenger,
pubmed-meshheading:19369471-Synovial Fluid,
pubmed-meshheading:19369471-Synovial Membrane,
pubmed-meshheading:19369471-Vascular Endothelial Growth Factor A,
pubmed-meshheading:19369471-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
The hypoxic synovial environment regulates expression of vascular endothelial growth factor and osteopontin in juvenile idiopathic arthritis.
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pubmed:affiliation |
Laboratory of Molecular Biology, Department of Pediatrics, G. Gaslini Institute, Genova, Italy. mariacarlabosco@ospedale-gaslini.ge.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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