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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2009-6-24
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pubmed:abstractText |
A strong association between retinal degeneration and obesity has been shown in humans. However, the molecular basis of increased risk for retinal degeneration in obesity is unknown. Thus, an animal model with obesity and retinal degeneration would greatly aid the understanding of obesity-associated retinal degeneration. The retinal abnormalities in a novel rat model (WNIN-Ob) with spontaneously developed obesity are described.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1552-5783
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3456-63
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pubmed:meshHeading |
pubmed-meshheading:19369235-Animals,
pubmed-meshheading:19369235-Disease Models, Animal,
pubmed-meshheading:19369235-Female,
pubmed-meshheading:19369235-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:19369235-Gene Expression Regulation,
pubmed-meshheading:19369235-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:19369235-Male,
pubmed-meshheading:19369235-Membrane Proteins,
pubmed-meshheading:19369235-Microscopy, Fluorescence,
pubmed-meshheading:19369235-Obesity,
pubmed-meshheading:19369235-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:19369235-Opsins,
pubmed-meshheading:19369235-Rats,
pubmed-meshheading:19369235-Rats, Wistar,
pubmed-meshheading:19369235-Retina,
pubmed-meshheading:19369235-Retinal Degeneration,
pubmed-meshheading:19369235-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19369235-Rhodopsin
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pubmed:year |
2009
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pubmed:articleTitle |
A novel rat model with obesity-associated retinal degeneration.
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pubmed:affiliation |
National Institute of Nutrition, Hyderabad, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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