Linked Life Data

19369112

Source:http://linkedlifedata.com/resource/pubmed/id/19369112

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2009-5-11
pubmed:abstractText
The recognition of plant pathogens activates local defense responses and triggers a long-lasting systemic acquired resistance (SAR) response. Activation of SAR requires the hormone salicylic acid (SA), which induces SA-responsive gene expression. Recent data link changes in gene expression to chromatin remodeling, such as histone modifications and histone replacement. Here, we propose a model in which recruitment of chromatin-modifying complexes to SA-responsive loci controls their basal and SA-induced expression. Basal repression of these loci requires the post-translational modifier SUMO (SMALL UBIQUITIN-LIKE MODIFIER). This is of particular relevance because SUMO conjugation has been shown to control the activity, assembly and disassembly of chromatin-modifying complexes to transcription complexes. Chromatin remodeling could be instrumental for priming of SA-responsive loci to enable their enhanced reactivation upon subsequent pathogen attack.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1360-1385
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
286-94
pubmed:dateRevised
2009-9-24
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Does chromatin remodeling mark systemic acquired resistance?
pubmed:affiliation
Laboratory of Phytopathology, Wageningen University, Binnenhaven 5, 6709 PD Wageningen, The Netherlands.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't