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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-4-16
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pubmed:abstractText |
The urinary bladder is an ideal organ for topical treatment. A substantial number of bladder cancer patients are resistant to conventional intravesical therapy. In search of new agents, antisense oligonucleotides (AS-ON) may be interesting candidates. The availability and toxicity as well as the effectivity of AS-ON after intravesical instillation in different rodent models were examined.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0258-851X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
13-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19368119-Administration, Intravesical,
pubmed-meshheading:19368119-Animals,
pubmed-meshheading:19368119-Antineoplastic Agents,
pubmed-meshheading:19368119-Cell Line, Tumor,
pubmed-meshheading:19368119-Cell Proliferation,
pubmed-meshheading:19368119-Dose-Response Relationship, Drug,
pubmed-meshheading:19368119-Female,
pubmed-meshheading:19368119-Injections, Intravenous,
pubmed-meshheading:19368119-Ki-67 Antigen,
pubmed-meshheading:19368119-Longevity,
pubmed-meshheading:19368119-Male,
pubmed-meshheading:19368119-Mice,
pubmed-meshheading:19368119-Mice, Inbred C57BL,
pubmed-meshheading:19368119-Neoplasm Transplantation,
pubmed-meshheading:19368119-Oligonucleotides, Antisense,
pubmed-meshheading:19368119-Rats,
pubmed-meshheading:19368119-Rats, Sprague-Dawley,
pubmed-meshheading:19368119-Toxicity Tests, Acute,
pubmed-meshheading:19368119-Tumor Markers, Biological,
pubmed-meshheading:19368119-Urinary Bladder,
pubmed-meshheading:19368119-Urinary Bladder Neoplasms
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pubmed:articleTitle |
In vivo studies on the availability and toxicity of antisense oligonucleotides in bladder cancer.
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pubmed:affiliation |
Department of Urology, University of Lübeck, Lübeck, Germany.
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pubmed:publicationType |
Journal Article
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