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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-11-6
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pubmed:abstractText |
Genetics may be involved in the pathophysiology of vasovagal syncope. The 3A/4A polymorphism of the EDN1 gene affects the expression of endothelin-1, and the H323H T/C polymorphism of the EDNRA gene encoding for the endothelin type A receptor has been associated with cardiovascular pathologies. As the endothelin system participates in the regulation of cardiovascular homeostasis, the aim of this study was to analyse the role of these genetic variants in influencing tilt-induced vasovagal syncope.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1619-1560
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
347-54
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pubmed:meshHeading |
pubmed-meshheading:19367425-Adult,
pubmed-meshheading:19367425-Alleles,
pubmed-meshheading:19367425-Endothelin-1,
pubmed-meshheading:19367425-Female,
pubmed-meshheading:19367425-Gene Frequency,
pubmed-meshheading:19367425-Genetic Predisposition to Disease,
pubmed-meshheading:19367425-Genotype,
pubmed-meshheading:19367425-Heterozygote,
pubmed-meshheading:19367425-Homozygote,
pubmed-meshheading:19367425-Humans,
pubmed-meshheading:19367425-Male,
pubmed-meshheading:19367425-Middle Aged,
pubmed-meshheading:19367425-Polymorphism, Genetic,
pubmed-meshheading:19367425-Receptor, Endothelin A,
pubmed-meshheading:19367425-Syncope, Vasovagal,
pubmed-meshheading:19367425-Tilt-Table Test
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pubmed:year |
2009
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pubmed:articleTitle |
Endothelin system polymorphisms in tilt test-induced vasovagal syncope.
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pubmed:affiliation |
Emergency and Organ Transplantation Department, University of Bari, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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