Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2009-4-27
pubmed:abstractText
Chitosan, a naturally occurring cationic polyelectrolyte, restores the adsorption of the clinical lung surfactant Survanta to the air-water interface in the presence of albumin at much lower concentrations than uncharged polymers such as polyethylene glycol. This is consistent with the positively charged chitosan forming ion pairs with negative charges on the albumin and lung surfactant particles, reducing the net charge in the double-layer, and decreasing the electrostatic energy barrier to adsorption to the air-water interface. However, chitosan, like other polyelectrolytes, cannot perfectly match the charge distribution on the surfactant, which leads to patches of positive and negative charge at net neutrality. Increasing the chitosan concentration further leads to a reduction in the rate of surfactant adsorption consistent with an over-compensation of the negative charge on the surfactant and albumin surfaces, which creates a new repulsive electrostatic potential between the now cationic surfaces. This charge neutralization followed by charge inversion explains the window of polyelectrolyte concentration that enhances surfactant adsorption; the same physical mechanism is observed in flocculation and re-stabilization of anionic colloids by chitosan and in alternate layer deposition of anionic and cationic polyelectrolytes on charged colloids.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-10228100, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-10368337, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-10934097, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-11029372, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-11423403, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-11509723, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-11704608, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-11737935, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-11806925, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-12380007, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-12959931, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-14747325, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-14762935, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-15454404, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-15585679, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-15671432, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-15807622, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-15923228, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-16006630, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-16055934, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-16236739, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-16394785, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-16864690, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-17040987, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-17416614, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-17419586, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-17543939, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-17575474, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-17630796, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-17662121, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-18036553, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-18067258, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-18487188, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-3233711, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-7604278, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-8134836, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-8332910, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-8592666, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-8982283, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-9168053, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-9563762, http://linkedlifedata.com/resource/pubmed/commentcorrection/19366599-9609406
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:volume
1788
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1033-43
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Mechanisms of polyelectrolyte enhanced surfactant adsorption at the air-water interface.
pubmed:affiliation
Department of Chemical Engineering, University of California, Santa Barbara, CA 93106-5080, USA.
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't
More...