Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2009-5-8
pubmed:abstractText
Oseltamivir phosphate (1) was synthesized from (-)-shikimic acid through a short and practical synthetic route via eight steps in 47% overall yield. In addition, the highly regioselective and stereoselective nucleophilic replacement of OMs by the N(3) group in the third and seventh steps has been studied in detail, and the reaction conditions were optimized.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1520-6904
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3970-3
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
A short and practical synthesis of oseltamivir phosphate (Tamiflu) from (-)-shikimic acid.
pubmed:affiliation
Department of Pharmaceutical Engineering, School of Pharmacy, East China University of Science and Technology, P.O. Box 363, 130 Mei-Long Road, Shanghai 200237, People's Republic of China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't