Source:http://linkedlifedata.com/resource/pubmed/id/19366236
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2009-5-8
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pubmed:abstractText |
Oseltamivir phosphate (1) was synthesized from (-)-shikimic acid through a short and practical synthetic route via eight steps in 47% overall yield. In addition, the highly regioselective and stereoselective nucleophilic replacement of OMs by the N(3) group in the third and seventh steps has been studied in detail, and the reaction conditions were optimized.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1520-6904
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3970-3
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pubmed:meshHeading | |
pubmed:year |
2009
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pubmed:articleTitle |
A short and practical synthesis of oseltamivir phosphate (Tamiflu) from (-)-shikimic acid.
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pubmed:affiliation |
Department of Pharmaceutical Engineering, School of Pharmacy, East China University of Science and Technology, P.O. Box 363, 130 Mei-Long Road, Shanghai 200237, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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