Linked Life Data

19361834

Source:http://linkedlifedata.com/resource/pubmed/id/19361834

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-5-25
pubmed:abstractText
The effects of particle size on the bioavailability of estrogenic chemicals in the sediments from the Yeongsan River and its tributaries in South Korea were evaluated for 2006 and 2007. Samples for chemical analysis and bioassays were collected from 6 sampling sites during both dry and rainy seasons. The pore water of the sediment samples was extracted, and estrogenic chemicals were eluted using a liquid-liquid extraction (LLE) method. Concentrations of 4-nonylphenol (NP), 4-tert-octylphenol (OP), bisphenol A (BPA), estrone (E1), 17beta-estradiol (E2), 17 alpha-ethynylestradiol (EE2) and genistein (Gen) were analyzed by gas chromatography-mass spectrometry (GC-MS). To evaluate bioavailability, hepatic vitellogenin (Vtg) concentrations of male Japanese medaka were measured after exposure to the sediment or its fractions for 7d. NP, BPA and E2 were detected in all the sediment sample extracts from the Yeongsan River and its tributaries. The concentrations of NP in the sedimentary samples ranged from 60 to 400 ngg(-1) on a dry weight basis. Similarly, OP and E2 were detected in nearly all the sediment extracts, with concentrations of 13 and 26 ngg(-1), respectively. According to the bioassay test results, all the sediment samples significantly induced Vtg in male fish after 7d of exposure. Fractionation of sediments into different size-classes (i.e., particle size >1 microm, particle size <1 microm) eliminated bioavailable estrogenic activity, but fine particles of less than 1microm in size increased the absorption of E2 from E2-amended sediment particle fractions. Consequently, the study suggested that the presence of particles and its interaction in the water environment might change the bioavailability of estrogenic chemicals.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1879-1298
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
395-401
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
The effect of particle size on the bioavailability of estrogenic chemicals from sediments.
pubmed:affiliation
Department of Environmental Science and Engineering, Gwangju Institute of Science and Technology, 1-Oryongdong, Bukgu, Gwangju 500-712, South Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't