rdf:type |
|
lifeskim:mentions |
umls-concept:C0007570,
umls-concept:C0021853,
umls-concept:C0031928,
umls-concept:C0078741,
umls-concept:C0220825,
umls-concept:C1173118,
umls-concept:C1333524,
umls-concept:C1333525,
umls-concept:C1705674,
umls-concept:C1706127,
umls-concept:C1883709
|
pubmed:issue |
8
|
pubmed:dateCreated |
2009-8-20
|
pubmed:abstractText |
In the clinical management of celiac disease, new noninvasive tools for evaluation of intestinal damage are needed for diagnosis and for follow-up of diet effects. Fatty acid binding proteins (FABP) are potentially useful for this purpose as these are small cytosolic proteins present in enterocytes and sensitive markers for intestinal mucosal damage. First, the distribution and microscopic localization of FABP in the healthy human intestine was examined. Second, levels of circulating FABP were measured in patients with celiac disease before and after introducing a gluten-free diet (GFD) and in healthy controls.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1539-2031
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
43
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
727-33
|
pubmed:meshHeading |
pubmed-meshheading:19359998-Adolescent,
pubmed-meshheading:19359998-Adult,
pubmed-meshheading:19359998-Celiac Disease,
pubmed-meshheading:19359998-Child,
pubmed-meshheading:19359998-Child, Preschool,
pubmed-meshheading:19359998-Diet, Gluten-Free,
pubmed-meshheading:19359998-Enterocytes,
pubmed-meshheading:19359998-Fatty Acid-Binding Proteins,
pubmed-meshheading:19359998-Female,
pubmed-meshheading:19359998-Humans,
pubmed-meshheading:19359998-Infant,
pubmed-meshheading:19359998-Infant, Newborn,
pubmed-meshheading:19359998-Intestinal Mucosa,
pubmed-meshheading:19359998-Male,
pubmed-meshheading:19359998-Middle Aged,
pubmed-meshheading:19359998-Pilot Projects,
pubmed-meshheading:19359998-Young Adult
|
pubmed:year |
2009
|
pubmed:articleTitle |
A pilot study on the noninvasive evaluation of intestinal damage in celiac disease using I-FABP and L-FABP.
|
pubmed:affiliation |
Department of Surgery, University Hospital Maastricht & Nutrition and Toxicology Research Institute, Maastricht University, Maastricht, the Netherlands.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
|