Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2009-7-1
pubmed:abstractText
Magnetic resonance elastography (MRE) measurements of shear stiffness (mu) in a spherical phantom experiencing both static and cyclic pressure variations were compared to those derived from an established pressure-volume (P-V)-based model. A spherical phantom was constructed using a silicone rubber composite of 10 cm inner diameter and 1.3 cm thickness. A gradient echo MRE sequence was used to determine mu within the phantom at static and cyclic pressures ranging from 55 to 90 mmHg. Average values of mu using MRE were obtained within a region of interest and were compared to the P-V-derived estimates. Under both static and cyclic pressure conditions, the P-V- and MRE-based estimates of mu ranged from 98.2 to 155.1 kPa and 96.2 to 150.8 kPa, respectively. Correlation coefficients (R(2)) of 0.98 and 0.97 between the P-V and MRE-based estimates of shear stiffness measurements were obtained. For both static and cyclic pressures, MRE-based measures of mu agree with those derived from a P-V model, suggesting that MRE can be used as a new, noninvasive method of assessing mu in sphere-like fluid-filled organs such as the heart.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1522-2594
pubmed:author
pubmed:copyrightInfo
(c) 2009 Wiley-Liss, Inc.
pubmed:issnType
Electronic
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
135-40
pubmed:dateRevised
2011-1-17
pubmed:meshHeading
pubmed-meshheading:19353657-Algorithms, pubmed-meshheading:19353657-Blood Pressure, pubmed-meshheading:19353657-Cardiac Volume, pubmed-meshheading:19353657-Computer Simulation, pubmed-meshheading:19353657-Elasticity Imaging Techniques, pubmed-meshheading:19353657-Humans, pubmed-meshheading:19353657-Image Enhancement, pubmed-meshheading:19353657-Image Interpretation, Computer-Assisted, pubmed-meshheading:19353657-Imaging, Three-Dimensional, pubmed-meshheading:19353657-Magnetic Resonance Imaging, pubmed-meshheading:19353657-Models, Cardiovascular, pubmed-meshheading:19353657-Pattern Recognition, Automated, pubmed-meshheading:19353657-Phantoms, Imaging, pubmed-meshheading:19353657-Reproducibility of Results, pubmed-meshheading:19353657-Sensitivity and Specificity, pubmed-meshheading:19353657-Stress, Mechanical, pubmed-meshheading:19353657-Ventricular Function, Left
pubmed:year
2009
pubmed:articleTitle
MR elastography as a method for the assessment of myocardial stiffness: comparison with an established pressure-volume model in a left ventricular model of the heart.
pubmed:affiliation
Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA.
pubmed:publicationType
Journal Article, Comparative Study, Evaluation Studies, Research Support, N.I.H., Extramural, Validation Studies