|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2009-8-18
|
|
pubmed:abstractText |
Survivin is undetectable in normal adult tissues, but has been shown to be overexpressed in various cancers and has been regarded as a marker of malignancy. Polymorphisms which increase the expression of survivin are potential risk factors for esophageal carcinogenesis. The aim of this study is to genotype the survivin promoter polymorphisms namely -31G/C, -241T/C, -625G/C, and -644T/C in esophageal squamous cell cancer patients and controls and to identify a possible association between individual genetic variation and susceptibility to esophageal squamous cell carcinoma (ESCC).
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
1432-1335
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
135
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1341-9
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:19352701-Adenocarcinoma,
pubmed-meshheading:19352701-Aged,
pubmed-meshheading:19352701-Asian Continental Ancestry Group,
pubmed-meshheading:19352701-Carcinoma, Adenosquamous,
pubmed-meshheading:19352701-Carcinoma, Squamous Cell,
pubmed-meshheading:19352701-Case-Control Studies,
pubmed-meshheading:19352701-Esophageal Neoplasms,
pubmed-meshheading:19352701-Female,
pubmed-meshheading:19352701-Haplotypes,
pubmed-meshheading:19352701-Humans,
pubmed-meshheading:19352701-Inhibitor of Apoptosis Proteins,
pubmed-meshheading:19352701-Lymphatic Metastasis,
pubmed-meshheading:19352701-Male,
pubmed-meshheading:19352701-Microtubule-Associated Proteins,
pubmed-meshheading:19352701-Middle Aged,
pubmed-meshheading:19352701-Neoplasm Staging,
pubmed-meshheading:19352701-Polymerase Chain Reaction,
pubmed-meshheading:19352701-Polymorphism, Genetic,
pubmed-meshheading:19352701-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:19352701-Prognosis,
pubmed-meshheading:19352701-Promoter Regions, Genetic,
pubmed-meshheading:19352701-Survival Rate
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Polymorphisms of survivin promoter are associated with risk of esophageal squamous cell carcinoma.
|
|
pubmed:affiliation |
Department of Medical Genetics, College of Basic Medical Science, Third Military Medical University, Chongqing 400038, People's Republic of China.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
