Source:http://linkedlifedata.com/resource/pubmed/id/19351214
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2009-4-8
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pubmed:abstractText |
Ideally, tests that predict the risk of cancer recurrence should be capable of guiding treatment decisions that are both therapeutically effective and cost effective. This paper evaluates the cost effectiveness of two tools that identify patients at high risk for biochemical (prostate-specific antigen) recurrence of prostate cancer after prostatectomy, the hypothesis being that accurate classification of high-risk patients will allow more appropriate use of secondary (adjuvant/salvage) treatment and may improve on current clinical practice. These risk-prediction tools are the Kattan postoperative nomogram, which uses clinicopathologic features, and the Prostate Px test, which employs additional morphometric and immunofluorescence features of the prostate specimen to predict risk of biochemical recurrence. These tools were trained on patients treated at the Memorial Sloan-Kettering Cancer Center (996 patients for the nomogram, 342 patients for the Prostate Px test).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1177-1062
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
31-47
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pubmed:meshHeading |
pubmed-meshheading:19351214-Cost-Benefit Analysis,
pubmed-meshheading:19351214-Decision Support Techniques,
pubmed-meshheading:19351214-Disease Progression,
pubmed-meshheading:19351214-Humans,
pubmed-meshheading:19351214-Male,
pubmed-meshheading:19351214-Markov Chains,
pubmed-meshheading:19351214-Models, Economic,
pubmed-meshheading:19351214-Neoplasm Recurrence, Local,
pubmed-meshheading:19351214-Patient Selection,
pubmed-meshheading:19351214-Postoperative Period,
pubmed-meshheading:19351214-Prostate-Specific Antigen,
pubmed-meshheading:19351214-Prostatectomy,
pubmed-meshheading:19351214-Prostatic Neoplasms,
pubmed-meshheading:19351214-Quality-Adjusted Life Years,
pubmed-meshheading:19351214-Radiotherapy, Adjuvant,
pubmed-meshheading:19351214-Risk
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pubmed:year |
2009
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pubmed:articleTitle |
Cost effectiveness of risk-prediction tools in selecting patients for immediate post-prostatectomy treatment.
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pubmed:affiliation |
Aureon Laboratories, Inc., Yonkers, New York 10701, USA. valentina.bayer@aureon.com
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pubmed:publicationType |
Journal Article
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