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rdf:type |
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lifeskim:mentions |
umls-concept:C0004112,
umls-concept:C0010453,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0166417,
umls-concept:C0205112,
umls-concept:C0386482,
umls-concept:C0439799,
umls-concept:C0851285,
umls-concept:C1314939,
umls-concept:C1882151
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pubmed:issue |
23-24
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pubmed:dateCreated |
2009-5-26
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pubmed:abstractText |
Recently, we demonstrated that cultured mouse astrocytes exhibited basal channel opening of P2X7 receptor (P2X7R) in the absence of any exogenous ligand, but the regulatory mechanism involved was not elucidated. Since our preliminary experiments suggested possible involvement of peroxisome proliferator-activated receptor (PPAR) gamma in the regulation, we examined whether PPAR gamma regulated P2X7R basal channel opening in mouse astrocytes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1879-0631
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
5
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
825-31
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19348833-Animals,
pubmed-meshheading:19348833-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:19348833-Astrocytes,
pubmed-meshheading:19348833-Cells, Cultured,
pubmed-meshheading:19348833-Ion Channels,
pubmed-meshheading:19348833-Mice,
pubmed-meshheading:19348833-PPAR gamma,
pubmed-meshheading:19348833-Purinergic P2 Receptor Agonists,
pubmed-meshheading:19348833-Rats,
pubmed-meshheading:19348833-Rats, Wistar,
pubmed-meshheading:19348833-Receptors, Purinergic P2,
pubmed-meshheading:19348833-Receptors, Purinergic P2X7
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pubmed:year |
2009
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pubmed:articleTitle |
Possible involvement of PPAR gamma in the regulation of basal channel opening of P2X7 receptor in cultured mouse astrocytes.
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pubmed:affiliation |
Department of Environmental Biochemistry, Kyoto Pharmaceutical University, 5 Nakauchi-cho, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan. nagasawa@mb.kyoto-phu.ac.jp
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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