Source:http://linkedlifedata.com/resource/pubmed/id/19346782
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2009-4-6
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pubmed:abstractText |
Hepatitis B virus (HBV) replicates via RNA intermediates, which could serve as targets for RNA interference (RNAi). Vector-mediated short-hairpin RNA (shRNA) can induce sustained RNAi in comparison to small interfering RNA. Lentiviral vector is known to induce prolonged RNAi with high transduction efficiency. In this study, we sought to test the in vitro efficacy of shRNA delivered by a lentiviral vector in suppressing the replication of HBV.
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pubmed:commentsCorrections | |
pubmed:language |
kor
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1738-222X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-24
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pubmed:meshHeading |
pubmed-meshheading:19346782-Cell Line, Tumor,
pubmed-meshheading:19346782-Genetic Vectors,
pubmed-meshheading:19346782-Hepatitis B virus,
pubmed-meshheading:19346782-Humans,
pubmed-meshheading:19346782-Lentivirus,
pubmed-meshheading:19346782-RNA, Viral,
pubmed-meshheading:19346782-RNA Interference,
pubmed-meshheading:19346782-Trans-Activators,
pubmed-meshheading:19346782-Virus Replication
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pubmed:year |
2009
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pubmed:articleTitle |
[Inhibition of in vitro hepatitis B virus replication by lentivirus-mediated short-hairpin RNA against HBx].
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pubmed:affiliation |
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Seoul National University Bungdang Hospital, Seongnam, Korea. kimjw@snubh.org.
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pubmed:publicationType |
Journal Article,
English Abstract
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