Linked Life Data

19345363

Source:http://linkedlifedata.com/resource/pubmed/id/19345363

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2009-5-18
pubmed:abstractText
Tooth enamel is the stiffest tissue in the human body with a well-organized microstructure. Developmental diseases, such as enamel hypomineralisation, have been reported to cause marked reduction in the elastic modulus of enamel and consequently impair dental function. We produce evidence, using site-specific transmission electron microscopy (TEM), of difference in microstructure between sound and hypomineralised enamel. Built upon that, we develop a mechanical model to explore the relationship of the elastic modulus of the mineral-protein composite structure of enamel with the thickness of protein layers and the direction of mechanical loading. We conclude that when subject to complex mechanical loading conditions, sound enamel exhibits consistently high stiffness, which is essential for dental function. A marked decrease in stiffness of hypomineralised enamel is caused primarily by an increase in the thickness of protein layers between apatite crystals and to a lesser extent by an increase in the effective crystal orientation angle.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1873-2380
pubmed:author
pubmed:issnType
Electronic
pubmed:day
29
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1075-80
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Effect of microstructure upon elastic behaviour of human tooth enamel.
pubmed:affiliation
Center for Integrated Nanotechnologies, Los Alamos, NM 87545, USA. z.xie@ecu.edu.au
pubmed:publicationType
Journal Article