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rdf:type |
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lifeskim:mentions |
umls-concept:C0003069,
umls-concept:C0008266,
umls-concept:C0009221,
umls-concept:C0017262,
umls-concept:C0018270,
umls-concept:C0034987,
umls-concept:C0185117,
umls-concept:C0220825,
umls-concept:C0486616,
umls-concept:C0542341,
umls-concept:C0678594,
umls-concept:C0795635,
umls-concept:C2003939,
umls-concept:C2698650,
umls-concept:C2911684
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pubmed:dateCreated |
2009-5-6
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pubmed:abstractText |
Transgenic chloroplasts are potential bioreactors for recombinant protein production, especially for achievement of high levels of protein expression and proper folding. Production of therapeutic proteins in leaves provides transgene containment by elimination of reproductive structures. Therefore, in this study, human Insulin like Growth Factor-1 is expressed in transgenic chloroplasts for evaluation of structural identity and function.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-10325399,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-10700152,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-10706548,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-11531335,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-12042861,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-12582236,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-1287665,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-1349669,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-15067115,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-15359602,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-16299323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-16327810,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-16410352,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-17000998,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-17147606,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-17184221,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-17207252,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-17309678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-17368018,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-17420457,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-17420459,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-17440039,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-17490448,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-17490449,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-17944820,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-18056863,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-18388956,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-18505806,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-18642268,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-6338496,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-7051784,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-7758431,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-8077337,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-8818276,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-8897021,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-9052777,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-9097850,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-9108541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-9352873,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-9384559,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-9501165,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19344517-9788349
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1472-6750
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
33
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:19344517-Base Sequence,
pubmed-meshheading:19344517-Cell Proliferation,
pubmed-meshheading:19344517-Chloroplasts,
pubmed-meshheading:19344517-Escherichia coli,
pubmed-meshheading:19344517-Gene Expression Regulation,
pubmed-meshheading:19344517-Humans,
pubmed-meshheading:19344517-Insulin-Like Growth Factor I,
pubmed-meshheading:19344517-Molecular Sequence Data,
pubmed-meshheading:19344517-Plant Leaves,
pubmed-meshheading:19344517-Plants, Genetically Modified,
pubmed-meshheading:19344517-Recombinant Proteins,
pubmed-meshheading:19344517-Regulatory Sequences, Nucleic Acid,
pubmed-meshheading:19344517-Tobacco,
pubmed-meshheading:19344517-Transgenes
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pubmed:year |
2009
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pubmed:articleTitle |
Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and function.
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pubmed:affiliation |
Department of Molecular Biology and Microbiology, University of Central Florida, College of Medicine, Orlando, FL 32816-2364, USA. daniell@mail.ucf.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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