rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-4-6
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pubmed:abstractText |
Human follicle-stimulating hormone (hFSH; follitropin alfa) can be employed therapeutically to induce ovarian follicular development in assisted reproduction treatments. Current recombinant hFSH (r-hFSH) preparations available for clinical use are labeled either in terms of the bioactivity expressed in international units (IU) or in mass (microg). Several clinical trials have tried to assess the clinical implications of the physicochemical improvements in the dosing of follitropin alfa filled by mass (FbM). The aim of this study was to perform a meta-analysis of previous studies in order to assess the efficacy and safety of ovarian stimulation using follitropin alfa FbM compared with follitropin alfa filled by international units (FbIU).
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1173-8804
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37-42
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pubmed:meshHeading |
pubmed-meshheading:19344190-Chemistry, Pharmaceutical,
pubmed-meshheading:19344190-Drug Administration Schedule,
pubmed-meshheading:19344190-Embryo Transfer,
pubmed-meshheading:19344190-Female,
pubmed-meshheading:19344190-Fertility Agents, Female,
pubmed-meshheading:19344190-Fertilization in Vitro,
pubmed-meshheading:19344190-Follicle Stimulating Hormone, Human,
pubmed-meshheading:19344190-Glycoprotein Hormones, alpha Subunit,
pubmed-meshheading:19344190-Humans,
pubmed-meshheading:19344190-Ovulation,
pubmed-meshheading:19344190-Ovulation Induction,
pubmed-meshheading:19344190-Quality Control,
pubmed-meshheading:19344190-Quality Indicators, Health Care,
pubmed-meshheading:19344190-Recombinant Proteins,
pubmed-meshheading:19344190-Treatment Outcome
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pubmed:year |
2009
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pubmed:articleTitle |
Outcomes of new quality standards of follitropin alfa on ovarian stimulation: meta-analysis of previous studies.
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pubmed:affiliation |
Agencia de Evaluación de Tecnologías Sanitarias, Instituto de Salud Carlos III, Ministerio de Sanidad y Consumo, Madrid, Spain. zuleika@isciii.es
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't,
Meta-Analysis
|