Source:http://linkedlifedata.com/resource/pubmed/id/19343362
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
2009-11-12
|
| pubmed:databankReference | |
| pubmed:abstractText |
Permethrin is the most widely used pediculicide, but evidence of resistance from several countries and anecdotal reports from Germany suggest that permethrin lotion is now less effective. We designed a randomized, controlled, parallel group trial involving 100 participants with active head louse infestation to investigate the activity of a coconut and anise spray and to see whether permethrin lotion is still effective, using two applications of product 9 days apart. The spray was significantly more successful (41/50, 82.0%) cures compared with permethrin (21/50, 42.0%; p < 0.0001, difference 40.0%, 95% confidence interval of 22.5% to 57.5%). Per-protocol success was 83.3% and 44.7%, respectively. Thirty-three people reported irritant reactions following alcohol contact with excoriated skin. We concluded that, although permethrin lotion is still effective for some people, the coconut and anise spray can be a significantly more effective alternative treatment.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
1432-1076
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
169
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
55-62
|
| pubmed:meshHeading |
pubmed-meshheading:19343362-Administration, Topical,
pubmed-meshheading:19343362-Adolescent,
pubmed-meshheading:19343362-Adult,
pubmed-meshheading:19343362-Animals,
pubmed-meshheading:19343362-Child,
pubmed-meshheading:19343362-Child, Preschool,
pubmed-meshheading:19343362-Dose-Response Relationship, Drug,
pubmed-meshheading:19343362-Double-Blind Method,
pubmed-meshheading:19343362-Female,
pubmed-meshheading:19343362-Follow-Up Studies,
pubmed-meshheading:19343362-Germany,
pubmed-meshheading:19343362-Humans,
pubmed-meshheading:19343362-Male,
pubmed-meshheading:19343362-Middle Aged,
pubmed-meshheading:19343362-Pediculus,
pubmed-meshheading:19343362-Permethrin,
pubmed-meshheading:19343362-Pimpinella,
pubmed-meshheading:19343362-Plant Oils,
pubmed-meshheading:19343362-Plant Preparations,
pubmed-meshheading:19343362-Scalp Dermatoses,
pubmed-meshheading:19343362-Treatment Outcome,
pubmed-meshheading:19343362-Young Adult
|
| pubmed:year |
2010
|
| pubmed:articleTitle |
Clinical trial showing superiority of a coconut and anise spray over permethrin 0.43% lotion for head louse infestation, ISRCTN96469780.
|
| pubmed:affiliation |
Medical Entomology Centre, Insect Research & Development Limited, 6 Quy Court, Colliers Lane, Stow-cum-Quy, Cambridge CB25 9AU, UK. ian@insectresearch.com
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|