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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1991-12-13
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pubmed:abstractText |
This study focused on the potent cytotoxic effect that mitoxantrone produces on Ehrlich ascites tumour cells. Host mice treated with mitoxantrone showed a life span three times higher than control non-treated host mice. Mitoxantrone also showed a potent cytotoxic effect on Ehrlich cells incubated in vitro for only a few hours. Studies on the effect of mitoxantrone on a plasma membrane redox system showed that mitoxantrone inhibits this activity, which is apparently related to cell proliferation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0263-6484
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
95-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1934315-Animals,
pubmed-meshheading:1934315-Carcinoma, Ehrlich Tumor,
pubmed-meshheading:1934315-Cell Division,
pubmed-meshheading:1934315-Cell Membrane,
pubmed-meshheading:1934315-Cell Transformation, Neoplastic,
pubmed-meshheading:1934315-Female,
pubmed-meshheading:1934315-Mice,
pubmed-meshheading:1934315-Mitoxantrone,
pubmed-meshheading:1934315-NADH, NADPH Oxidoreductases,
pubmed-meshheading:1934315-Oxidation-Reduction,
pubmed-meshheading:1934315-Tumor Cells, Cultured
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pubmed:year |
1991
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pubmed:articleTitle |
Mitoxantrone toxicity on Ehrlich ascites tumour cells: inhibition of the transplasma membrane redox activity.
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pubmed:affiliation |
Laboratorio de Bioquimica, Facultad de Ciencias, Universidad de Málaga, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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