Source:http://linkedlifedata.com/resource/pubmed/id/19342331
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-4-3
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pubmed:abstractText |
A quick wireless label-free detection of disease-related C-reactive proteins (CRPs) using a 200-microm-long microelectromechanical systems (MEMS) microcantilever housed in a 7 x 7 mm(2) reaction chamber with a safe reusable feature is reported. The assay time ranges from about 30 min to 3 h, depending on accuracy. The deflection of the microcantilever due to specific CRP-antiCRP binding is detected using a position-sensitive detector. The converted bio-signal is transmitted by a custom designed wireless amplitude-shift-keying (ASK) transceiver IC fabricated in a 0.18 microm CMOS process. CRP concentrations from 1 microg/mL to 500 microg/mL can be detected. A 0.2-Hz 1-V ac signal instead of traditional bases/acids is applied to the bio-MEMS sensor to unbind the CRP from the microcantilever for reusability.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1558-2531
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pubmed:author |
pubmed-author:ChenChun-HaoCH,
pubmed-author:ChenHsiao-ChinHC,
pubmed-author:ChouNai-KuanNK,
pubmed-author:HuangLong-SunLS,
pubmed-author:HwangRong-ZhangRZ,
pubmed-author:LinShi-MingSM,
pubmed-author:LinYo-ShengYS,
pubmed-author:LinYu-TsoYT,
pubmed-author:LuShey-ShiSS,
pubmed-author:WangYiao-HongYH,
pubmed-author:YangYu-CheYC,
pubmed-author:YuShih-AnSA
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pubmed:issnType |
Electronic
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
462-70
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:19342331-Biosensing Techniques,
pubmed-meshheading:19342331-C-Reactive Protein,
pubmed-meshheading:19342331-Cardiovascular Diseases,
pubmed-meshheading:19342331-Dimethylpolysiloxanes,
pubmed-meshheading:19342331-Equipment Design,
pubmed-meshheading:19342331-Equipment Reuse,
pubmed-meshheading:19342331-Humans,
pubmed-meshheading:19342331-Micro-Electrical-Mechanical Systems,
pubmed-meshheading:19342331-Monitoring, Ambulatory,
pubmed-meshheading:19342331-Nanotechnology,
pubmed-meshheading:19342331-Signal Processing, Computer-Assisted
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pubmed:year |
2009
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pubmed:articleTitle |
A wireless bio-MEMS sensor for C-reactive protein detection based on nanomechanics.
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pubmed:affiliation |
Graduate Institute of Electronics Engineering, National Taiwan University, Taipei, Taiwan 106, ROC.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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