Source:http://linkedlifedata.com/resource/pubmed/id/19340954
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2009-4-1
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pubmed:databankReference | |
pubmed:abstractText |
A gene encoding a receptor for activated protein kinase C1 homolog has been isolated from the shrimp, Penaeus monodon (Pm-RACK1). The full length Pm-RACK1 cDNA has 957 bp, and an open reading frame encoding a protein of 318 amino acid residues. The protein contains seven WD40 repeats and shares approximately 78% identity with vertebrate RACK1. In adult shrimp, Pm-RACK1 transcripts were detected in all tissues. During WSSV infection, Pm-RACK1 was upregulated in hepatopancreas, stomach and hemocytes. We identified Pm-RACK1 as a specific cellular target protein for VP9, a nonstructural protein of WSSV. The interaction of these two proteins may be involved in mediating intracellular VP9 functions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1095-9947
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
509-14
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pubmed:meshHeading |
pubmed-meshheading:19340954-Amino Acid Sequence,
pubmed-meshheading:19340954-Animals,
pubmed-meshheading:19340954-Gene Expression Profiling,
pubmed-meshheading:19340954-Gene Expression Regulation,
pubmed-meshheading:19340954-Molecular Sequence Data,
pubmed-meshheading:19340954-Penaeidae,
pubmed-meshheading:19340954-Receptors, Cell Surface,
pubmed-meshheading:19340954-Sequence Alignment,
pubmed-meshheading:19340954-Two-Hybrid System Techniques,
pubmed-meshheading:19340954-Viral Proteins,
pubmed-meshheading:19340954-White spot syndrome virus 1
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pubmed:year |
2009
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pubmed:articleTitle |
Identification of a receptor for activated protein kinase C1 (Pm-RACK1), a cellular gene product from black tiger shrimp (Penaeus monodon) interacts with a protein, VP9 from the white spot syndrome virus.
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pubmed:affiliation |
Center for Genomics and Bioinformatics Research, Faculty of Science, Prince of Songkla University, 15 Karnjanavanit Road, Songkhla 90110, Thailand. tonganunt@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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