Source:http://linkedlifedata.com/resource/pubmed/id/19340655
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2009-6-26
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pubmed:abstractText |
Interleukin-13 (IL-13) is a T(H)2 cytokine that plays a crucial role in the pathophysiology of tumors and favor tumor growth and recurrence by negative regulation of tumor immunosurveillance. In the present investigation, we have determined the IL-13 level in the serum and ascitic fluid of the DL-bearing host and the possible source of IL-13 in the ascitic fluid. IL-13 level was elevated in serum and ascitic fluid of host bearing a transplantable T-cell lymphoma. DL cells as well as tumor-associated macrophages express and secrete IL-13 in the milieu, which provide further insight for DL-induced immunosuppression in a tumor-bearing host.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1532-4192
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
641-9
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pubmed:meshHeading |
pubmed-meshheading:19340655-Animals,
pubmed-meshheading:19340655-Ascites,
pubmed-meshheading:19340655-Cell Line, Tumor,
pubmed-meshheading:19340655-Female,
pubmed-meshheading:19340655-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19340655-Immune Tolerance,
pubmed-meshheading:19340655-Interleukin-13,
pubmed-meshheading:19340655-Lymphoma, T-Cell,
pubmed-meshheading:19340655-Macrophages,
pubmed-meshheading:19340655-Mice,
pubmed-meshheading:19340655-Mice, Inbred BALB C,
pubmed-meshheading:19340655-RNA, Messenger,
pubmed-meshheading:19340655-Time Factors,
pubmed-meshheading:19340655-Tumor Escape,
pubmed-meshheading:19340655-Up-Regulation
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pubmed:year |
2009
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pubmed:articleTitle |
Overexpression of interleukin-13 in a murine T-cell lymphoma: a possible factor of DL-induced immunosuppression and tumor progression.
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pubmed:affiliation |
Immunology Lab, Department of Zoology, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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