Source:http://linkedlifedata.com/resource/pubmed/id/19340128
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2009-4-2
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pubmed:abstractText |
Second-harmonic-generation (SHG) microscopy is an interesting new tool for observing dermal collagen fiber in skin. However, conventional SHG microscopy using a mode-locked Ti:sapphire laser suffers from low penetration depth and a slow image acquisition rate caused by scattering and absorption in tissue, making it difficult to use for in vivo applications on human skin. We develop an SHG microscope equipped with a mode-locked Cr:forsterite laser with a long wavelength and compare its imaging characteristics with that of a Ti:sapphire-laser-based SHG microscope for the measurement of dermal collagen fiber in animal and human skins. The results indicate the suitability of the Cr:forsterite laser-based SHG microscope for in vivo imaging of human skin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Aluminum Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Chromium,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen,
http://linkedlifedata.com/resource/pubmed/chemical/Silicon Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/forsterite
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1539-4522
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
D88-95
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pubmed:meshHeading |
pubmed-meshheading:19340128-Adult,
pubmed-meshheading:19340128-Aluminum Oxide,
pubmed-meshheading:19340128-Animals,
pubmed-meshheading:19340128-Chromium,
pubmed-meshheading:19340128-Collagen,
pubmed-meshheading:19340128-Dermis,
pubmed-meshheading:19340128-Humans,
pubmed-meshheading:19340128-Lasers,
pubmed-meshheading:19340128-Male,
pubmed-meshheading:19340128-Microscopy, Confocal,
pubmed-meshheading:19340128-Middle Aged,
pubmed-meshheading:19340128-Silicon Compounds
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pubmed:year |
2009
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pubmed:articleTitle |
Ex vivo and in vivo second-harmonic-generation imaging of dermal collagen fiber in skin: comparison of imaging characteristics between mode-locked Cr:forsterite and Ti:sapphire lasers.
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pubmed:affiliation |
Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama-cho, Toyonaka, Osaka 560-8531, Japan. t-yasui@me.es.osaka-u.ac.jp
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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