Source:http://linkedlifedata.com/resource/pubmed/id/19333549
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2009-5-8
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| pubmed:abstractText |
Deduced amino acid sequence and phylogenetic analyses of a group A rotavirus G9P[6] strain (designated as mcs/13-07), detected from a 3-year-old child in Eastern India, revealed a VP8* closely related to porcine P[6] strains (P[6] sublineage 1D), and the VP7 clustered with G9 lineage-III strains. To our knowledge, this is the first report of human P[6] strain clustering in sublineage Id. Thus, to further characterize the evolutionary diversity of strain mcs/13-07, all gene segments were analyzed. VP6 and NSP4 exhibited genetic relatedness to Wa-like human subgroup II strains, while VP1-3, NSP1-3 and NSP5 were closely related to porcine strains. Based on the new classification system of rotaviruses, mcs/13-07 revealed a G9-P[6]-I1-R1-C1-M1-A8-N1-T1-E1-H1 genotype with close similarity to human Wa-like and porcine Gottfried strains. Therefore, considering the porcine-like or porcine origin of multiple gene segments, it might be tempting to assume that strain mcs/13-07 represents a rare instance of whole-virus transmission from pig to human, after which the virus evolved with time. Alternatively, it is possible that strain mcs/13-07 resulted from multiple reassortment events involving human subgroup II and porcine P[6] strains. Nevertheless, detection of strain mcs/13-07 provides further evidence for complex interspecies transmission events, which are frequent in developing countries.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
1432-8798
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| pubmed:author |
pubmed-author:BagchiParikshitP,
pubmed-author:ChattopadhyayShiladityaS,
pubmed-author:Chawla-SarkarMamtaM,
pubmed-author:DuttaDipanjanD,
pubmed-author:DuttaPhalguniP,
pubmed-author:GhoshSouvikS,
pubmed-author:KobayashiNobumichiN,
pubmed-author:KrishnanTriveniT,
pubmed-author:MukherjeeAnupamA,
pubmed-author:NagashimaShigeoS,
pubmed-author:NaikTrailokya NathTN
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| pubmed:issnType |
Electronic
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| pubmed:volume |
154
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
733-46
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| pubmed:meshHeading |
pubmed-meshheading:19333549-Animals,
pubmed-meshheading:19333549-Child, Preschool,
pubmed-meshheading:19333549-Evolution, Molecular,
pubmed-meshheading:19333549-Genome, Viral,
pubmed-meshheading:19333549-Humans,
pubmed-meshheading:19333549-India,
pubmed-meshheading:19333549-Male,
pubmed-meshheading:19333549-Phylogeny,
pubmed-meshheading:19333549-RNA, Viral,
pubmed-meshheading:19333549-RNA-Binding Proteins,
pubmed-meshheading:19333549-Rotavirus,
pubmed-meshheading:19333549-Rotavirus Infections,
pubmed-meshheading:19333549-Sequence Analysis, RNA,
pubmed-meshheading:19333549-Sequence Homology, Amino Acid,
pubmed-meshheading:19333549-Species Specificity,
pubmed-meshheading:19333549-Swine,
pubmed-meshheading:19333549-Swine Diseases,
pubmed-meshheading:19333549-Viral Nonstructural Proteins,
pubmed-meshheading:19333549-Zoonoses
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| pubmed:year |
2009
|
| pubmed:articleTitle |
Full genomic analysis of a human group A rotavirus G9P[6] strain from Eastern India provides evidence for porcine-to-human interspecies transmission.
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| pubmed:affiliation |
Division of Virology, National Institute of Cholera and Enteric Diseases, P-33 C.I.T. Road Scheme XM, Beliaghata, Kolkata 700010, West Bengal, India.
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|