Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-5-4
pubmed:abstractText
Creation of a transjugular intrahepatic portosystemic shunt (TIPS) requires passage of a needle toward a moving target that is only seen transiently by X-ray prior to needle passage. Intraoperative, 3D target localization would facilitate target access and improve the safety of the procedure. The clinical assumption is that patients undergoing the TIPS procedure possess rigid, cirrhotic livers that undergo only intraoperative translation without significant deformation or rotation. Based upon this assumption, we hypothesize that the position of any unseen, 3D target point within the liver can be determined intraoperatively by precalculation of the relative positions of the target point to a different 3D point that can be tracked intraoperatively. This paper examines this hypothesis using intraoperatively acquired, biplane, X-ray images of seven patients. In six, we tracked the effects of cardiac and respiratory motion, and in three the effects of needle pressure. Methods involved reconstruction of 3D vessel bifurcation and other trackable intrahepatic points from biplane angiograms, measurement of liver deformation by examining changing distances between these 3D points over time, and comparison of expected to actual displacements of these points with respect to a fixed reference point in the liver. We conclude that, for the rigid livers associated with patients undergoing TIPS, that there is less intraoperative deformation than previously reported by other groups addressing healthy liver deformation, and that the location of an unseen target can be predicted within 3mm accuracy.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-10357476, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-10834493, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-11265875, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-11875086, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-12582982, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-15095845, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-16193801, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-16209172, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-16614155, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-16685965, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-16793168, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-16797100, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-17414843, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-9314363, http://linkedlifedata.com/resource/pubmed/commentcorrection/19332378-9448179
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1361-8423
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
519-29
pubmed:dateRevised
2011-9-26
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Vessel target location estimation during the TIPS procedure.
pubmed:affiliation
CASILab, Division of Neurosurgery, University of North Carolina-CH, Chapel Hill, NC 27599, USA.
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural