Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1991-11-26
pubmed:abstractText
Oestrogens are administered to women as contraceptive agents and as treatment for menopausal symptoms. This article reviews the epidemiological evidence concerning the risk of breast cancer related to both types of medication. It is generally accepted that long-term; high-dose menopausal oestrogen administration without accompanying progestogen is associated with a moderate increase in breast cancer risk; and that combined oral contraceptives reduce the risk of benign breast disease (as well as ovarian and endometrial cancer). The effect of oral contraceptives on breast cancer risk, however, is less certain. Possible reasons for the lack of agreement between recently conducted case-control studies are discussed, concentrating specifically on the effect of possible latency, being the sum of a prolonged induction plus pre-clinical period, in explaining the discrepancies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0007-1420
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
484-92
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Oestrogens and breast cancer: exogenous hormones.
pubmed:affiliation
Department of Public Health and Primary Care, Radcliffe Infirmary, Oxford, UK.
pubmed:publicationType
Journal Article, Review