In this issue of Molecular Cell, Jani et al. (2009) present the crystal structure of a region of TREX2, thereby providing a physical framework for how the transcription and export machineries might cooperate to "gate" genes to the nuclear pore.
Department of Biochemistry and Biophysics, University of California, San Francisco, 600 16th Street, Genentech Hall, San Francisco, CA 94143-2200, USA.
