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rdf:type |
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lifeskim:mentions |
umls-concept:C0001645,
umls-concept:C0004358,
umls-concept:C0018802,
umls-concept:C0031928,
umls-concept:C0035820,
umls-concept:C0087111,
umls-concept:C0597357,
umls-concept:C0599894,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
3
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pubmed:dateCreated |
2009-3-30
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pubmed:abstractText |
Autoantibodies directed against the beta1-adrenergic receptor exert agonist-like actions by inducing receptor uncoupling and cause myocardial damage as well as fatal ventricular arrhythmias. Previous studies have shown that beta-blockers can modulate these actions of the autoantibodies. We investigated the influence of such autoantibodies in patients with congestive heart failure (CHF) receiving beta-blocker therapy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic beta-1 Receptor...,
http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic beta-Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Autoantibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Carbazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Metoprolol,
http://linkedlifedata.com/resource/pubmed/chemical/Natriuretic Peptide, Brain,
http://linkedlifedata.com/resource/pubmed/chemical/Norepinephrine,
http://linkedlifedata.com/resource/pubmed/chemical/Propanolamines,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Adrenergic, beta-1,
http://linkedlifedata.com/resource/pubmed/chemical/carvedilol
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1532-8414
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
224-32
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19327624-Adrenergic beta-1 Receptor Antagonists,
pubmed-meshheading:19327624-Adrenergic beta-Antagonists,
pubmed-meshheading:19327624-Autoantibodies,
pubmed-meshheading:19327624-Carbazoles,
pubmed-meshheading:19327624-Diastole,
pubmed-meshheading:19327624-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:19327624-Female,
pubmed-meshheading:19327624-Heart Failure,
pubmed-meshheading:19327624-Heart Rate,
pubmed-meshheading:19327624-Heart Ventricles,
pubmed-meshheading:19327624-Humans,
pubmed-meshheading:19327624-Male,
pubmed-meshheading:19327624-Metoprolol,
pubmed-meshheading:19327624-Middle Aged,
pubmed-meshheading:19327624-Natriuretic Peptide, Brain,
pubmed-meshheading:19327624-Norepinephrine,
pubmed-meshheading:19327624-Pilot Projects,
pubmed-meshheading:19327624-Propanolamines,
pubmed-meshheading:19327624-Receptors, Adrenergic, beta-1,
pubmed-meshheading:19327624-Stroke Volume,
pubmed-meshheading:19327624-Systole
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pubmed:year |
2009
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pubmed:articleTitle |
A pilot study on the role of autoantibody targeting the beta1-adrenergic receptor in the response to beta-blocker therapy for congestive heart failure.
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pubmed:affiliation |
Cardiology Division, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
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