Source:http://linkedlifedata.com/resource/pubmed/id/19327422
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
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| pubmed:dateCreated |
2009-3-30
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| pubmed:abstractText |
Elevated glucose level on admission is common in patients with acute coronary syndrome (ACS) and has been shown to be a strong predictor of adverse outcome in patients both with and without diabetes. The purpose of the study was to assess the impact of admission glucose on in-hospital mortality in patients with non-ST-segment elevation ACS treated in hospitals without on-site invasive facilities. We identified 807 patients with non-ST-segment elevation ACS treated conservatively in the 29 hospitals participating in the Krakow Registry of Acute Coronary Syndromes; 763 patients with complete admission glucose data were stratified according to admission glucose level. Of these, 24.2% had admission glucose level <5, 50.6% had a level 5 to 6.9, 10.9% had a level 7 to 8.9, 6.7% had a level 9 to 10.9, and 7.6% had a level > or =11 mmol/L. In-hospital mortality was higher in patients with higher admission glucose (admission glucose <5, 5 to 6.9, 7 to 8.9, 9 to 10.9, and > or =11 mmol/L: 0.5%, 2.6%, 7.2%, 9.8%, and 24.1% respectively, p <0.0001). Similarly, significant mortality difference was observed in patient subgroups stratified by admission glucose level and presence of diabetes mellitus and cardiogenic shock. Independent predictors of in-hospital death were age, cardiogenic shock, admission glucose, chronic obstructive pulmonary disease, and renal insufficiency. In conclusion, admission glucose level is a strong predictor of in-hospital death in patients with non-ST-segment elevation ACS remaining in hospitals without on-site invasive facilities. Impact of admission glucose on mortality is independent of diabetes and cardiogenic shock presence.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Apr
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| pubmed:issn |
1879-1913
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:day |
1
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| pubmed:volume |
103
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
954-8
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| pubmed:meshHeading |
pubmed-meshheading:19327422-Acute Coronary Syndrome,
pubmed-meshheading:19327422-Aged,
pubmed-meshheading:19327422-Blood Glucose,
pubmed-meshheading:19327422-Diabetes Mellitus,
pubmed-meshheading:19327422-Diagnostic Tests, Routine,
pubmed-meshheading:19327422-Electrocardiography,
pubmed-meshheading:19327422-Female,
pubmed-meshheading:19327422-Follow-Up Studies,
pubmed-meshheading:19327422-Hospital Mortality,
pubmed-meshheading:19327422-Humans,
pubmed-meshheading:19327422-Male,
pubmed-meshheading:19327422-Middle Aged,
pubmed-meshheading:19327422-Patient Admission,
pubmed-meshheading:19327422-Poland,
pubmed-meshheading:19327422-Prognosis,
pubmed-meshheading:19327422-Prospective Studies,
pubmed-meshheading:19327422-Reproducibility of Results,
pubmed-meshheading:19327422-Survival Rate,
pubmed-meshheading:19327422-Vasodilator Agents
|
| pubmed:year |
2009
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| pubmed:articleTitle |
Impact of admission glucose level and presence of diabetes mellitus on mortality in patients with non-ST-segment elevation acute coronary syndrome treated conservatively.
|
| pubmed:affiliation |
2nd Department of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
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| pubmed:publicationType |
Journal Article,
Comparative Study,
Multicenter Study
|