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pubmed-article:19327403pubmed:abstractTextMulti-modal brain imaging was used to examine the relation between individual differences in resting-state striatal dopamine D2 binding and the magnitude of prefrontal BOLD activation during updating of long-term memory (LTM) representations. Increased activity in the left prefrontal cortex was observed when LTM updating was required, and there was a positive correlation between striatal D2 activity and the magnitude of left prefrontal activity during updating. These findings support predictions from neurocomputational models of a relation of dopaminergic neurotransmission to transient cognitive operations and related brain activity.lld:pubmed
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pubmed-article:19327403pubmed:articleTitleStriatal dopamine D2 binding is related to frontal BOLD response during updating of long-term memory representations.lld:pubmed
pubmed-article:19327403pubmed:affiliationDepartment of Radiation Sciences, Diagnostic Radiology, Umeå University, Sweden. Lars.Nyberg@diagrad.umu.selld:pubmed
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