rdf:type |
|
lifeskim:mentions |
umls-concept:C0013030,
umls-concept:C0205123,
umls-concept:C0338207,
umls-concept:C0423909,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C0871261,
umls-concept:C1167622,
umls-concept:C1514861,
umls-concept:C1552599,
umls-concept:C1655730,
umls-concept:C1704632,
umls-concept:C1704787,
umls-concept:C1705491,
umls-concept:C1706817,
umls-concept:C1882932,
umls-concept:C2911692
|
pubmed:issue |
4
|
pubmed:dateCreated |
2009-5-25
|
pubmed:abstractText |
Multi-modal brain imaging was used to examine the relation between individual differences in resting-state striatal dopamine D2 binding and the magnitude of prefrontal BOLD activation during updating of long-term memory (LTM) representations. Increased activity in the left prefrontal cortex was observed when LTM updating was required, and there was a positive correlation between striatal D2 activity and the magnitude of left prefrontal activity during updating. These findings support predictions from neurocomputational models of a relation of dopaminergic neurotransmission to transient cognitive operations and related brain activity.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
1095-9572
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:day |
15
|
pubmed:volume |
46
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1194-9
|
pubmed:meshHeading |
pubmed-meshheading:19327403-Aged,
pubmed-meshheading:19327403-Brain Mapping,
pubmed-meshheading:19327403-Corpus Striatum,
pubmed-meshheading:19327403-Humans,
pubmed-meshheading:19327403-Image Interpretation, Computer-Assisted,
pubmed-meshheading:19327403-Magnetic Resonance Imaging,
pubmed-meshheading:19327403-Male,
pubmed-meshheading:19327403-Memory,
pubmed-meshheading:19327403-Middle Aged,
pubmed-meshheading:19327403-Models, Neurological,
pubmed-meshheading:19327403-Receptors, Dopamine D2,
pubmed-meshheading:19327403-Tomography, Emission-Computed, Single-Photon
|
pubmed:year |
2009
|
pubmed:articleTitle |
Striatal dopamine D2 binding is related to frontal BOLD response during updating of long-term memory representations.
|
pubmed:affiliation |
Department of Radiation Sciences, Diagnostic Radiology, Umeå University, Sweden. Lars.Nyberg@diagrad.umu.se
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|