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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2009-7-29
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pubmed:abstractText |
Müller glia are essential for maintaining retinal homeostasis and exhibit neuroprotective and deleterious responses during retinal degeneration. Having the ability to visualize and genetically manipulate Müller glia in vivo will facilitate a better understanding of how these cells contribute to these processes. The goal of this study was to determine whether regulatory elements of the retinaldehyde binding protein 1 (Rlbp1; formerly Cralbp) gene can drive robust Müller glial gene expression in vivo.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1552-5783
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3996-4003
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pubmed:meshHeading |
pubmed-meshheading:19324864-Animals,
pubmed-meshheading:19324864-Carrier Proteins,
pubmed-meshheading:19324864-Female,
pubmed-meshheading:19324864-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:19324864-Gene Expression Regulation,
pubmed-meshheading:19324864-Genotype,
pubmed-meshheading:19324864-Green Fluorescent Proteins,
pubmed-meshheading:19324864-Male,
pubmed-meshheading:19324864-Mice,
pubmed-meshheading:19324864-Mice, Inbred C57BL,
pubmed-meshheading:19324864-Mice, Inbred CBA,
pubmed-meshheading:19324864-Mice, Transgenic,
pubmed-meshheading:19324864-Microscopy, Confocal,
pubmed-meshheading:19324864-Neuroglia,
pubmed-meshheading:19324864-Promoter Regions, Genetic,
pubmed-meshheading:19324864-Retinal Degeneration,
pubmed-meshheading:19324864-Retinal Neurons,
pubmed-meshheading:19324864-Retinaldehyde
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pubmed:year |
2009
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pubmed:articleTitle |
Rlbp1 promoter drives robust Müller glial GFP expression in transgenic mice.
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pubmed:affiliation |
Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, UT 84132, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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