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| pubmed-article:19324536 | lifeskim:mentions | umls-concept:C0086045 | lld:lifeskim |
| pubmed-article:19324536 | lifeskim:mentions | umls-concept:C0028768 | lld:lifeskim |
| pubmed-article:19324536 | lifeskim:mentions | umls-concept:C0061465 | lld:lifeskim |
| pubmed-article:19324536 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:19324536 | lifeskim:mentions | umls-concept:C1335671 | lld:lifeskim |
| pubmed-article:19324536 | lifeskim:mentions | umls-concept:C1415300 | lld:lifeskim |
| pubmed-article:19324536 | lifeskim:mentions | umls-concept:C0392756 | lld:lifeskim |
| pubmed-article:19324536 | lifeskim:mentions | umls-concept:C1521725 | lld:lifeskim |
| pubmed-article:19324536 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:19324536 | pubmed:dateCreated | 2009-4-6 | lld:pubmed |
| pubmed-article:19324536 | pubmed:abstractText | In this preliminary study, 16 psychotropic-naïve pediatric patients with obsessive-compulsive disorder (OCD) were studied using magnetic resonance spectroscopy (MRS) and genotyped for six candidate polymorphisms in two glutamate system genes. A significant association was identified between the rs1019385 polymorphism of the glutamate receptor, ionotropic, N-methyl-d-aspartate 2B (GRIN2B) and decreased anterior cingulate cortex (ACC) glutamatergic concentration (Glx) but not with occipital Glx. These results suggest that GRIN2B may be associated with Glx in the ACC, a region consistently implicated in OCD. | lld:pubmed |
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| pubmed-article:19324536 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:19324536 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19324536 | pubmed:month | May | lld:pubmed |
| pubmed-article:19324536 | pubmed:issn | 0165-1781 | lld:pubmed |
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| pubmed-article:19324536 | pubmed:owner | NLM | lld:pubmed |
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| pubmed-article:19324536 | pubmed:dateRevised | 2011-4-1 | lld:pubmed |
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| pubmed-article:19324536 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19324536 | pubmed:articleTitle | Glutamate receptor gene (GRIN2B) associated with reduced anterior cingulate glutamatergic concentration in pediatric obsessive-compulsive disorder. | lld:pubmed |
| pubmed-article:19324536 | pubmed:affiliation | Program in Genetics and Genomic Biology, Hospital for Sick Children, Toronto, ON, Canada M5G 1X8. paul.arnold@sickkids.ca | lld:pubmed |
| pubmed-article:19324536 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19324536 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:19324536 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:19324536 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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