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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-4-27
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pubmed:abstractText |
Fibroblast growth factor 2 (FGF2; basic fibroblast growth factor, b-FGF) and its main receptor FGFR-1 are important in both hemangiogenesis and lymphangiogenesis. Murine studies have indicated a close interplay between both FGF2 and platelet-derived growth factor-B (PDGF-B) as well as FGF2 and vascular endothelial growth factor-3 (VEGFR-3). This study investigates the prognostic impact of FGF2 and FGFR-1 in tumor cells and tumor stroma of resected non-small cell lung carcinomas (NSCLC) and explores the importance of their coexpression with VEGFR-3 or PDGF-B.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1556-1380
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
578-85
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pubmed:dateRevised |
2010-5-26
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pubmed:meshHeading |
pubmed-meshheading:19318994-Adenocarcinoma,
pubmed-meshheading:19318994-Adenocarcinoma, Bronchiolo-Alveolar,
pubmed-meshheading:19318994-Adult,
pubmed-meshheading:19318994-Aged,
pubmed-meshheading:19318994-Aged, 80 and over,
pubmed-meshheading:19318994-Carcinoma, Large Cell,
pubmed-meshheading:19318994-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:19318994-Carcinoma, Squamous Cell,
pubmed-meshheading:19318994-Female,
pubmed-meshheading:19318994-Fibroblast Growth Factor 2,
pubmed-meshheading:19318994-Humans,
pubmed-meshheading:19318994-Immunoenzyme Techniques,
pubmed-meshheading:19318994-Lung Neoplasms,
pubmed-meshheading:19318994-Male,
pubmed-meshheading:19318994-Middle Aged,
pubmed-meshheading:19318994-Prognosis,
pubmed-meshheading:19318994-Proto-Oncogene Proteins c-sis,
pubmed-meshheading:19318994-Receptor, Fibroblast Growth Factor, Type 1,
pubmed-meshheading:19318994-Retrospective Studies,
pubmed-meshheading:19318994-Stromal Cells,
pubmed-meshheading:19318994-Survival Rate,
pubmed-meshheading:19318994-Tissue Array Analysis,
pubmed-meshheading:19318994-Tumor Markers, Biological,
pubmed-meshheading:19318994-Vascular Endothelial Growth Factor Receptor-3
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pubmed:year |
2009
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pubmed:articleTitle |
Prognostic impact of fibroblast growth factor 2 in non-small cell lung cancer: coexpression with VEGFR-3 and PDGF-B predicts poor survival.
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pubmed:affiliation |
Institute of Clinical Medicine, University of Tromso, Norway. tom.donnem@uit.no
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pubmed:publicationType |
Journal Article
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