Source:http://linkedlifedata.com/resource/pubmed/id/19318811
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-3-25
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pubmed:abstractText |
Melanoma with rhabdoid features is an uncommon melanoma variant. Many questions remain regarding rhabdoid differentiation and whether this phenotype represents a common pathogenetic pathway from distinct tissue malignancies. We describe a case of primary melanoma illustrating rhabdoid features, a recurrent rhabdoid clone and its diagnostic challenges. Immunohistochemistry in this tumor frequently involves loss of melanoma specific markers, while Vimentin may display a paranuclear accentuation in keeping with reported ultrastructural features. This case documents rhabdoid differentiation within a primary tumor and recurrence of the presumed more aggressive rhabdoid clone.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1533-0311
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
200-4
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pubmed:meshHeading |
pubmed-meshheading:19318811-Aged,
pubmed-meshheading:19318811-Biological Markers,
pubmed-meshheading:19318811-Biopsy,
pubmed-meshheading:19318811-Cell Differentiation,
pubmed-meshheading:19318811-Clone Cells,
pubmed-meshheading:19318811-Humans,
pubmed-meshheading:19318811-Immunohistochemistry,
pubmed-meshheading:19318811-Male,
pubmed-meshheading:19318811-Melanoma,
pubmed-meshheading:19318811-Neoplasm Recurrence, Local,
pubmed-meshheading:19318811-Rhabdoid Tumor,
pubmed-meshheading:19318811-Skin Neoplasms,
pubmed-meshheading:19318811-Vimentin
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pubmed:year |
2009
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pubmed:articleTitle |
Primary rhabdoid melanoma with clonal recurrence.
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pubmed:affiliation |
Dermatopathology section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118, USA. bentallon@gmail.com
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pubmed:publicationType |
Journal Article,
Case Reports
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